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aeruginosa and Bcc isolates tested in their study were tobramycin in high-dose, which can be achieved by inhalation, added to meropenem plus a third intravenous antimicrobial agent (piperacillin/tazobactam, amikacin, ceftazidime, or cotrimoxazole) 60

Preliminary results show that after four weeks of regular IN therapy, functional skills improved, paving the way for a larger cohort study to assess the long-term safety and possible effectiveness of IN-insulin administration to treat and prevent functional decline in PD patients

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However, there are outstanding questions regarding the specific approach of manipulating transcriptional programs to induce neurogenesis