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Decrease in pain scores after vitamin B12 supplementation have been also reported in other types of pain such as peripheral neuropathy and post-chemotherapy musculoskeletal pain
2011 (PMID 21719467) reported that Nle1-angiotensin IV analogs promoted synaptogenesis and dendritic spine formation

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In infants, pyridoxine deficiency can cause irritability, abnormallyacute hearing, and seizures, which are unresponsive to anticonvulsants but respond to pyridoxine supplementation (, )
