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Description
Why Butyrate Matters
Spies M, Wolf SE, Barrow RE, Jeschke MG, Herndon DN
KPV suppresses this activation at nanomolar concentrations, meaning it works in very small amounts with high specificity
Passage of bile acids through the enterocyte activates FXR, which promotes the synthesis of fibroblast growth factor 19 (FGF19), which also circulates through the portal vein to the liver where it activates fibroblast growth factor-receptor 4 resulting in inhibition of bile acid synthesis
