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Mitochondrial oxidative stress is considered to be the predominant cellular event in APAP-induced liver injury

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higher abundances of Bacteroidetes and Proteobacteria and lower abundances of Firmicutes , Actinobacteria , and Fusobacteria have been observed during treatment with selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors [11]

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Meanwhile, there is evidence that estrogen inhibits signaling of several members of the cytokine receptor family, including prolactin, IL-6, and leptin (10)

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