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Thus, holohaptocorrin is not only involved in the formation of the hepatic store of vitamin B12, but it is also itself a reserve of circulating vitamin B12 (163)

The detailed interrelationships and interdependencies between substances that damage the epithelial barrier, the intestinal microbiota, the immune system, the development of inflammation, changes in cell function and ultimately the development of diseases, often located distantly from the intestine, remain unclear

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