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Values represented as mean SEM
The NFB pathway is initiated by the degradation of IB, enabling NF-B to translocate to the nucleus and promote the transcription of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which further damage endothelial cells and disrupt tight junction proteins (Figure 3) [188,189,190]
0.5 mg and 1 mg doses of once-weekly injectable semaglutide
10.3171/2020.6.SPINE20803 9.Yang MM , Riva-Cambrin J , Cunningham J , et al
