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Downregulation of ATP5A1, the ATP Synthase F1 Subunit Alpha [123], and ATP5G3, the ATP synthase F0 complex subunit C3 [124], was observed in the postmortem study of ASD patients in all examined regions [122], which could inhibit the activity of complex V [79] and promote the ETC breakdown due to opening of the mPTP [125, 126]

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May aid brain function To date, results are mixed, with one 2018 study reporting 1500mg of l-carnitine (as acetyl-l-carnitine) taken daily for 28 weeks improved brain function in those with dementia

More precisely, L-carnitine is essential for transporting long-chain fatty acids across the mitochondrial membrane, for subsequent fat breakdown and energy generation