buthionine sulfoximine glutathione mechanism of action Natural Compounds and Glutathione: Beyond Mere Antioxidants Buthionine Sulfoximine - an overview

et al., in which the authors reported the role of inducible nitric oxide synthase (iNOS) in the pathogenesis of steatohepatitis, with a protector role on increasing the expression of Heme oxygenase-1 (HO-1), similarly regulated by NRF-2 [44]

Here are some key concerns: Increased Oxidative Stress : A decrease in glutathione levels can lead to increased oxidative stress, which is associated with various chronic diseases, including cardiovascular disease, diabetes, and neurodegenerative disorders

Mol Pharmaceut 3(6):675685

There are specific formulations for oral use that allow for better stability and prevent degradation