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Insert in one smooth, deliberate motion (a quick, confident entry hurts less than a slow, hesitant one), deliver the dose steadily, then withdraw at the same angle you went in

Following an oral dose in dogs of 2.5 mg/kg (1.13 mg/lb), enrofloxacin reached 50% of its maximum serum concentration in 15 minutes and peak serum level was reached in one hour

The Centers for Disease Control analyzed and compared the blood tests of 7,300 such children