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Most proposed mechanisms at the molecular level have only been observed in cell systems or animal models, but not confirmed in humans

Chaudhuri, D
Structural changes have been observed in a cleft between the large and small domains, and we subsequently found that the K256Q mutant has a smaller substrate-binding pocket

To view a copy of this license, visit About this article Cite this article Begas, P., Liedgens, L., Moseler, A
