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6.2 Cancer treatment At the beginning of the 1950s, apitoxins influence on the colchicine-induced carcinogenic pathway was documented (Gajski et al., 2024)
Core nucleoid components such as TFAM, mitochondrial single-stranded DNA-binding protein (mtSSB), DNA polymerase gamma POLG, mitochondrial DNA-dependent RNA polymerase POLRMT, and Lon protease are essential for mtDNA packaging, maintenance, and transcription (Fig
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