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While aberrant ROS production can be detrimental to cellular health, ROS also serve as signaling molecules capable of regulating transcriptional events in the cell
40 nM elesclomol-Cu(II) resulted in a tenfold increase in intracellular Cu level in 2 h and triggered ABC1 cell death after 24 h (Tsvetkov et al., 2022)
Diabetics taking medications such as metformin, insulin, or sulfonylureas need caution
The expression of SLC22A4 can itself be modulated by other factors, including by PPAR- activity (439)
