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A significant fraction of the heme moeity may be converted to metabolites other than bilirubin, such as mesobilifuscins, that are excreted in the bile/feces and urine ( Heterozygote females are often considered only as carriers, leading to under-diagnosis of G6PD deficiency as the underlying cause of severe hyperbilirubinemia

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A: Oral glutathione is generally well-tolerated

In addition, these studies often focused on the cortex and subcortical regions such as the basal ganglia and thalamus