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It provides the primary nutrients known to be necessary for the breakdown of homocysteine into methionine and other metabolites, including vitamin B6 as pyridoxine and pyridoxal-5-phosphate (P5P), vitamin B12 as methylcobalamin, folate as 5-methyltetrahydrofolate (5-MTHF), trimethylglycine (TMG), and L-serine.* It is now enhanced with vitamin B2 as riboflavin-5-phosphate, Setria glutathione, zinc, and increased amounts of activated pyridoxal-5-phosphate.* Recommendation: Allergy Research Group suggests taking 1 capsule one or two times daily with meals, or as directed by a healthcare practitioner

10.1016/s0047-6374(00)00217-7 [DOI] [PubMed] [Google Scholar] 21.Anisimov VN, Arutjunyan AV, Khavinson VK

Nonetheless, future research should explore this issue further