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Research indicates that B7H3 can activate the AKT pathway and decrease sterol regulatory element binding protein 2-mediated cholesterol metabolism, thus inhibiting RSL3-mediated ferroptosis [162]

doi: 10.1177/1534735415588928 109 ApriokuJAmah-TariahF

Cheng, K
An animal study in 2024 has raised concerns about KD potentially promoting metastasis under certain conditions