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demonstrated that high glucose significantly promotes TGF-1 secretion in HK-2 renal tubular cells, triggering ferroptosis via the TGF-1/Smad3 signaling pathway, while sleeve gastrectomy alleviates the symptoms and progression of diabetic kidney disease by downregulating this pathway [135]

Gut 69 , 16911705 (2020)

Additionally, mulberry extract (0.18 and 0.9% mulberry extract for 12 weeks) reduces brain -amyloid levels and improves learning and memory in SAMP 8 mice (42)

FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors
