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4.1.Cisplatin and Paclitaxel Paclitaxel is a mitotic agent that binds preferentially to microtubules(Parness and Horwitz, 1981) and the resulting stabilization of microtubules inhibits the reorganization of the microtubule network

risks associated with indebtedness incurred in connection with the proposed merger, including the potential inability to access, or reduced access to, the capital markets or other capital resources or increased cost of borrowings, including as a result of a credit rating downgrade

However, if an imbalance occurs between ROS/RNS and the antioxidant enzymes, oxidative stress will ensue causing a toxic environment that can lead to damage of DNA, protein, and lipids [16]
