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Trials with high or unclear risk of bias in the first three criteria were deemed high risk

147,148 In animal research, noise trauma was found to lower brain taurine levels, 149 and taurine supplementation decreased noise-induced nerve activation
Studies increasingly point to creatine playing a broader role in supporting muscle performance, cellular energy, and brain health related to mental alertness, attention, and mood

Urinary biomarkers offer a promising avenue in this context, providing deeper insight into the complex and multifactorial pathophysiology of DKD
