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Notably, NAM serves as the substrate for NAD + synthesis in the salvage pathway (Pissios, 2017)

This diversity of presentation is one of the reasons seizures in children are frequently unrecognised or misattributed, particularly when they do not conform to the generalised tonic-clonic pattern that most people associate with the word. The International League Against Epilepsy classifies seizures first by their point of onset, as focal, generalised or unknown, and then by the predominant motor or non-motor features of the episode. Understanding this framework helps to explain why the clinical spectrum of seizures is so broad, and why accurate characterisation of a seizure episode is important for both diagnosis and management