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doi: 10.1111/dom.12423 127 YangYChoiPPSmithWWXuWMaDCordnerZAet al
doi: 10.1093/ajcn/84.6.1489
5 / 22 When Is a Mole a Problem
The IGF-1/PI3K/Akt signaling pathway is not only capable of activating anabolic pathways, but also of suppressing catabolic pathways, due to an inactivation of a specific transcription factor family called forkhead box-O transcription factors (FOXO) [53]
