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hypothesised that the oxidation of ET involves either a disulfide intermediate (similar to glutathione and glutathione disulfide), which is hydrolysed back to ET, generating ET-SO 3 H and hercynine as end products, or ET is directly oxidized into ET-SO 3 H as a stable end product 40

Mostofa MG, Ghosh A, Li ZG, Siddiqui MN, Fujita M, Tran LSP (2018) Methylglyoxala signaling molecule in plant abiotic stress responses

ROS are specific to aerobic cells and are usually produced in their metabolic processes

Furthermore, the complexity of IGF signalling is enhanced by the myriad of proteins which are activated downstream of it such as the Ras/Raf/MAPK and PI3K/AKT signalling pathways