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Aqueous humor samples were collected during trabeculectomy surgery or cataract surgery and analyzed with global metabolomics

Serine is regarded as an inflection in the glucose metabolic pathway

A new review centered specifically on mitochondrial ROS (mtROS) dyshomeostasis within the supraspinatus muscle-integrating its unique biomechanical unloading, ischemic microenvironment, and post-injury metabolic stress-is still lacking

This lactate shuttle not only fuels mitochondrial metabolism in cancer cells but also contributes to acidification of the extracellular environment, which promotes invasion, immune evasion, and angiogenesis (131, 136)