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Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia

In parallel, a growing number of clinical trials targeting aging are underway, providing increasing evidence for the safety and efficacy of these interventions (Wang K

SARS-CoV-2 infection requires a high basal energy expenditure for immune activation, hyper-inflammation (cytokine storm), anorexia followed by muscle loss, weakness, and fatigue 643

The activation of macrophages and lymphocytes which leads to a coordinated cytokine response is a hallmark of chronic inflammation (Germolec et al
