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doi: 10.1016/j.colsurfb.2018.11.025

Studies have shown that when amyloid-beta and tau are increased, the cells ability to neutralize oxidative stress and mitochondria specific ROS is decreased leading to further tau hyperphosphorylation and neurodegeneration (Alavi Naini and Soussi-Yanicostas 2015)

In contrast, a constant 50 M exposure of quinone (B) overwhelms blood and cytosolic GSH and Cys, showing no signs of recovery after a 10-hour time-span

10.1016/j.bmc.2024.117685
