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Under a heightened proteostatic burden, however, GRP94 can switch to an ATP hydrolysisindependent holding mode, buffering unfolded clients and preventing their aggregation until folding conditions improve
The extinction coefficient of the monitored chromophore needs to be experimentally determined as it can vary depending on the reaction conditions
The carbonylation in worker fat body reflects the oxidation of Vg as compared to other storage proteins, such that a direct relationship is evident in our results (Figure 7)
Neurotensin polyplex as an efficient carrier for delivering the human GDNF gene into nigral dopamine neurons of hemiparkinsonian rats
