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Kumar A, Singh LP, Harshan HM, Majumdar AC

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A narrative review

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(1) The researchers performed docking simulations and suggested that the tripeptide may form stable binding poses with VEGFR-2 through multiple hydrogen bonds, including interactions with residues such as LEU-37, LYS-117, CYS-116, and ASN-120

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Unlike earlier compounds that targeted only one or two receptors, this molecule activates three distinct pathways: glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors

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