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Description
5-Amino-1MQ works by inhibiting NNMT (the enzyme that degrades NAD+ precursors), whereas NMN and NR work by directly supplying NAD+ precursors
E., Hotamisligil G
The FDA's GRAS determination confirms safety for oral consumption as a food ingredient
Importantly, NNMT is a dominant component of the gene expression signature for sarcopenia, overexpression of which could lead to significantly reduced levels of NAD+ and associated declines in muscle mass, strength, and function that accompany aging
