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doi: 10.1080/15548627.2020.1810918 69 YangWSKimKJGaschlerMMPatelMShchepinovMSStockwellBR
Genome-wide methylation profiling of melanoma tissues and cell lines has demonstrated that the RIPK3 promoter region exhibits significantly higher CpG island hypermethylation in metastatic melanoma compared to primary lesions and normal melanocytes, a change that directly correlates with reduced RIPK3 mRNA and protein expression (99)
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