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Oral and topical glutathione serve different purposes

Therefore, a comprehensive synthesis of available evidence is needed to clarify whether non-invasive routes provide efficacy comparable to intramuscular therapy

Further exploration revealed that this was driven mainly by the difference between patients with ME/CFS and HCs (F = 9.589, p = 0.004), with ME/CFS patients showing higher lactate levels than controls, although a trend towards significant difference between patients with ME/CFS and long COVID was also noted (F = 4.031, p = 0.052)
