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Because its research-grade (rather than consumer-approved) and considering its ability to cross the blood brain barrier, the key is: start modestly, track your response, and adjust only when justified

Preliminary results show that after four weeks of regular IN therapy, functional skills improved, paving the way for a larger cohort study to assess the long-term safety and possible effectiveness of IN-insulin administration to treat and prevent functional decline in PD patients

These injections last just under a week, so it is recommended to receive the injections twice a week, and include a Vitamin B12 shot for maximum benefit

Sowinski et al