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Molecules (2023) 28:3389

With that, these results provide valuable insights into the impact of amyloid-like structures on NPCs phenotypes and behaviors, presenting a promising scaffold for future investigations into AD mechanisms and drug testing

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However, when endogenous tissue oxidant levels are high, NO can react with them to produce secondary oxidizing species that can promote membrane and lipoprotein lipid oxidation, which may further have proatherogenic effects ( Nitrogen dioxide ( NO 2 ) is not generated as a free radical within the body