how are b12 injections administered Treating Severe Vitamin Deficiency Will my B12 Injection Work
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However, if your body has trouble absorbing B12 due to digestive issues, pills may not be as effective

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Though it differs a bit from one person to another, the effects of B12 vitamins usually last around 48 hours to 72 hours after the initial injection

Proceedings of the National Academy of Sciences of the United States of America