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This suggests that breast cancer patients with ASS1 deficiency might be candidates for arginine starvation therapy

10.1016/j.redox.2025.103601 120 Van den BosscheJ.BaardmanJ.de WintherM

30 This finding shows that PR may be an effective regimen in humans and that it may delay aging by influencing the insulin/IGF-1 signaling pathway, an evolutionarily conserved mechanism that regulates longevity
