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Botulinum toxin (aka Botox) is one of the simplest yet most effective treatments for patients with synkinesis, facial asymmetry, and facial tightness resulting from Bells palsy and other causes

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However, the pooled analysis did not show significantly lower disability progression: 12-week worsening of disability was 5.2% in the ublituximab group compared to 5.9% in the teriflunomide group

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Beginners should start at 5 mg once per week and assess tolerance for two weeks before increasing

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