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Metabolic Studies in Obese Zucker Murine Models An early preclinical study evaluated the metabolic implications of AOD-9604 in obese Zucker rats, a validated rodent model of obesity characterized by leptin receptor deficiency and hyperphagia

doi: 10.1126/science.1193270 28 CosteB.XiaoB.SantosJ

The lack of protection and repair capabilities can leave nerves vulnerable to damage

Others report feeling a difference almost immediately
