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N -Methylation of Compounds 1.70 and 1.71 was achieved using the steps outlined in Figure 2 on resin using 1,8-diazabicyclo(5.4.0)undec-7-ene (DBU)

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For specific injuries like tennis elbow, this approach makes intuitive sense and aligns with how the peptide is most commonly used in research settings

So that, this technology is expected to become more widespread because of their advantages against other methods as chemical, with public health effects ( Magbanua et al., 2006 ), or catalysis with long exposure periods for achieving reasonable results of inactivation