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Unfortunately, in spite of a number of positive mechanistic observations, CCK-receptor antagonists were not further developed for the treatment of FD

Nippon Ganka Gakkai Zasshi 101 (8), 639643

These different outcomes could partly be due to the temporary nature of depleted CoQ 10 levels in healthy adults and athletes after their physical exertions, while the depleted CoQ 10 levels in elders are a result of their ages, illnesses, and metabolic statuses

Decreasing the dose in most cases can fix this
