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Although a Rieske-type microbial CntA / B enzyme was proposed to convert carnitine to TMA [20], recent studies argued against its role in TMA synthesis from carnitine in the human gut [11, 21]

During this period, no modifications in serum lipid profile and circulating leukocyte count were noted

The HTML:TML ratio was decreased by IDH1 inhibition and rescued by KG (Extended Data Fig
