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Description
To validate these findings, we examined the protein levels of key NOTCH pathway components (HEY1, HES1, and NOTCH1) by Western blot in LUAD cells with SLC25 A39 knockout (koSLC25 A39) and overexpression (oeSLC25A39)
The resultant effect of exposure to highly reactive intermediates is oxidative damage to proteins, lipids, and nucleic acids
Our findings provide new insights into the dose-dependent actions of GSNO and reinforce its translational potential as a NO-based therapeutic for myocardial protection
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