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Description
In metabolomics, metabolite set enrichment analysis is used to identify the altered metabolite sets (metabolic pathways) associated with phenotypes of interest, e.g., presence of fatigue, using algorithms which is run on a general metabolite network constructed based on public databases, i.e., KEGG (Kyoto Encyclopedia of Genes and Genomes) in the present study 57,58,59
coli subjected to treatment with CAZ revealed significant alterations in the concentrations of 43 metabolites, with 14 metabolites upregulated and 29 downregulated (Figure 2C)
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Other toxins that may also contribute to iodine deficiencies and thyroid dysfunction include nicotine, benzopyrenes, and hydroxylysine metabolites
