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On the other hand, FOXO4-DRI did not show significant toxicity in normal TM3 Leydig cells (Figure 5B5D), where expression of FOXO4 was low (Figure 3C3E)
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This increased energy efficiency not only supports weight management but also helps maintain lean muscle mass
Additionally, other issues, like liver disease, might become aggravated by fluctuating thyroid hormone levels, even when the liver cells are capable of handling their own levels of oxidative stress
