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The authors declare that it is a review-type article, so no experiments in animals or humans need to be declared

Rajesh Gupta, md

317 The mechanism of SGLT-is and GLP-1 on CVD benefits might be that they improve mitochondrial energy metabolism and reduces oxidative stress though activation of AMPK signaling pathways 318
VD Metabolism Genes and Blood 25(OH)VD Status in Humans The primary sources of cholecalciferol or vitamin D in humans are dermal synthesis and diet
