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10.1371/journal.pone.0107421 155

1999;276:E1136E1145

Mutations in this domain have been associated with severe hemolytic conditions requiring chronic transfusion support (Reisz et al., 2018)
Oxidative stress and neuronal loss Ferroptosis, an iron-dependent form of cell death distinct from apoptosis and necrosis, is primarily triggered by oxidative stress, a key pathological process in AD