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Moreover, methotrexate contained nanoparticulates, which revealed that nanoparticulates had a significant effect on reducing the IC50 up to four times that of the usual drug
However, this success starkly highlights the target dilemma for the approximately 90% of patients with sporadic ALS, where no single causative mutation exists (75)
Chronic GI inflammation with no clear diagnosis: Standard GI workup was negative, but the patient continues to experience bloating, food sensitivities, and post-meal fatigue
Their reactivity is based on the 1,3-dicarbonyl chemistry originally demonstrated with dimedone
