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Description
This occurs via the Bcl-2 family of proteins and the cysteine protease caspase family

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Posttranslational modification and regulation of glutamate-cysteine ligase by the ,-unsaturated aldehyde 4-hydroxy-2-nonenal

This damage allows low-density lipoproteins to enter the tunica intima, where they are oxidized and engulfed by macrophages to form foam cells
