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An increased ROS and MDA levels were observed with a subsequent decrease in thiol levels, CAT, and glutathione-S-transferase activities (129)
& Hayes, J
10.1039/D0CS00304B 53 ThomasE

What hEDS IS know for, though, is chronic acute pain, but it was only a few years after diganosis with hEDS that I learnt that B12 deficiency can also cause severe muscle pain
