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Description
IL-6 also suppresses osteoblast gene expressionsuch as ALP, Runx2, and osteocalcinthrough PI3K/Akt2 and MEK/ERK signaling, reducing new bone mineralization
These effects may not be directly caused by the vitamin B12 itself, but by the preservatives that are sometimes included in supplements
Haan, J
Failure of selenium-ace to improve osteoarthritis
