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doi: 10.1016/j.cct.2015.10.012
Grnert SC, Eckenweiler M, Haas D, Lindner M, Tsiakas K, Santer R, et al
131 The anti-diabetic drug metformin has also been shown to activate AMPK in the heart
The drug is associated with a high incidence of adverse reactions (excessive salivation and partial to complete loss of appetite) purportedly because of its brassy taste (2,3)
