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Description
290 Aging Older age is accompanied by an increasing level of oxidative stress, which is linked to endothelial inflammation and platelet activation
[DOI] [PubMed] [Google Scholar] 225.He B., Sui X., Yu B., Wang S., Shen Y., Cong H
Appl Catal B-Environ, 162, 319-326

Sun exposure , pollution, even inflammation these things switch those cells into high gear, which means more melanin and, usually, darker skin or hyperpigmentation
