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Description
For example, C247 of rhodanese is located at the intersection of the axes of two helices, which contribute a significant electrical field and lower the p K a of the thiol group (estimated to be 6.5) by 3.5 units, making this sulfur atom very nucleophilic

doi:10.1097/CCM.0b013e3181e8adcc
If you suspect gluten is causing your constipation, consider speaking with a healthcare professional to rule out celiac disease before cutting gluten from your diet

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